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Design of two complementary copolymers that work as a glue for cell-laden collagen gels

ChemComm, 56, 10545-10548 (2020).

Taihei Nishimoto, Ko Matsukawa, Kenichi Nagase, Hideko Kanazawa, Aya M. Akimoto*, and Ryo Yoshida*



We designed two types of copolymers that play a role of “polymeric glue”. They introduced surface adhesive functions to cell-laden collagen gels. The present study realised surface functionalisation of naturally derived hydrogels and suggested a novel method for manipulating living cells. This method is potentially useful for in vitro reconstruction of 3D living tissue since it enabled versatile and cytocompatible hydrogel surface modification by a simple procedure without any special equipment.

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